Areas of Expertise 

I bring expertise in the following key areas, focused on the development of ultrasound-responsive microbubbles for theranostic applications:

Engineering and physicochemical optimization of microbubbles for enhanced therapeutic performance

Investigation of the structural, chemical, and acoustic properties of lipid microbubbles, including encapsulation efficiency, cavitation behavior, and displacement in response to acoustic radiation force using microfluidic channels, to enable precise control over imaging performance and therapeutic efficacy. 

Elucidating microbubble–ultrasound interactions and pharmacokinetics to improve in vivo efficacy

Investigation of the mechanical, biological, and biophysical effects induced by microbubble–ultrasound interactions at the cellular and tissue levels, as a function of microbubble physicochemical properties, dosing parameters, and in vivo pharmacokinetic behavior. 

Development of targeted microbubbles for precision ultrasound molecular imaging

Development of ligand-functionalized microbubbles that selectively bind to disease-specific biomarkers using acoustic radiation force, enabling highly sensitive, real-time, and noninvasive molecular imaging.

Design of  microbubbles for controlled and efficient drug delivery

Engineering microbubbles for the encapsulation or co-delivery of therapeutic agents, enabling precise and localized release as well as enhanced cellular uptake through ultrasound-induced sonoporation.

Translational research

My approach is centered on translational research, aiming to bridge laboratory discoveries with clinically actionable solutions that directly benefit patients. This framework allows me to address real-world health challenges and generate meaningful societal impact.

Impactful Outcomes 

The most important result I deliver through my areas of expertise is the creation of transformative biomedical technologies that address real clinical needs, improving disease diagnosis, treatment, and therapeutic monitoring.